GTP-induced constriction by dynamin: Three-dimensional maps of dynamin in the non-constricted (left) and constricted (right) states (Chen et al, 2004). Dynamin undergoes a large conformational change upon GTP hydrolysis which leads to a significant constriction of underlying lipid bilayer.

Figure 5: GTP-induced constriction by dynamin: Three-dimensional maps of dynamin in the non-constricted (left) and constricted (right) states (Chen et al, 2004). Dynamin undergoes a large conformational change upon GTP hydrolysis which leads to a significant constriction of underlying lipid bilayer.